The San Francisco 49ers are in a tight spot with only three days until their Super Bowl LVIII battle against the Kansas City Chiefs. But win or lose, Niners linebackers coach Johnny Holland is enjoying every moment.
![]()
“Sunday is a great day because it’s game day,” Holland told CBS News. “But, you know, I now realize that every day is a great day. It taught me a lot about seeing life from a fresh perspective.”
After experiencing shoulder and rib pain five years ago, Holland was diagnosed with multiple myeloma, a rare and incurable blood cancer.
“Immediately, I started chemo treatment and went on every day, going to work every day and go get chemo once a week,” Holland told CBS News. “It probably took about six months to realize that, ‘this is pretty serious that you’re going through.'”

He is now a participant in a clinical trial at the University of California, San Francisco Medical Center, which is evaluating new medicines.
“Immunotherapy uses the body’s immune system to help fight cancer,” explained Samantha Shenoy, a nurse practitioner who is guiding Holland through each appointment. “To put it simply, one arm hooks to a cancer cell and the other to the body’s own T cells. So what it does is it basically boosts the body’s immune system, specifically its T cells, to help fight cancer.
“Patients living with myeloma live with a lot of uncertainty,” she said. “He faces that uncertainty with a really positive attitude.”
Also unexplained is why Black people account for one in every five new diagnoses, making Holland’s participation in the trial a game changer.
“It’s really important to have diversity within clinical trials so we can help answer some of these questions,” she said.